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Dott. Bonapace & C. will be at CPHI Milan 2026 from 6 to 8 October, showcasing a selection of its pharmaceutical machinery live at the Marchesini Group stand, 9A2, Hall H09.

The 2026 edition of CPHI Worldwide will be a particularly important occasion for Dott. Bonapace, as the company celebrates 80 years of experience in the development and manufacturing of pharmaceutical equipment.

Pharmaceutical machinery running live at CPHI Milan

Visitors to the Marchesini Group stand will have the opportunity to see several Dott. Bonapace machines operating live, offering a direct insight into the technologies used for different pharmaceutical manufacturing applications.

The machines on display will include the CPR-22 and CPR-18 SE rotary tablet presses, the IN-CAP SE and IN-CAP SIOLATED capsule filling machines, and the SUPP LINE with CU-1, BP-10 and BP-11, dedicated to suppository and ovule production.

The live demonstrations will showcase the flexibility of Dott. Bonapace solutions and their ability to address different production requirements, from specialised applications to small- and medium-scale pharmaceutical manufacturing.

Capsule filling and tablet compression

Among the solutions presented in Milan, the CPR-22 and CPR-18 SE will highlight Dott. Bonapace’s expertise in tablet compression technology.

The IN-CAP SE, meanwhile, represents the company’s approach to flexible capsule filling, while the IN-CAP SIOLATED brings the focus to contained applications where process protection and operator safety are key considerations.

Together, these machines demonstrate the breadth of Dott. Bonapace’s expertise in tablet presses, capsule filling technology and specialised pharmaceutical equipment.

Suppository and ovule production

The SUPP LINE, equipped with CU-1, BP-10 and BP-11, will also be demonstrated at CPHI Milan.

The system is designed for the production of suppositories and ovules, bringing together different stages of the production process in an integrated solution.

Its presence at CPHI highlights Dott. Bonapace’s experience in specialised pharmaceutical applications beyond conventional solid-dose manufacturing.

80 years of pharmaceutical expertise

CPHI Milan 2026 will have an additional meaning for Dott. Bonapace: 2026 marks the company’s 80th anniversary.

Since its foundation in 1946, Dott. Bonapace has developed specialised technologies for the pharmaceutical industry, building expertise across capsule filling, tablet compression, suppository and ovule production, containment and other pharmaceutical processing applications.

Eight decades of experience have shaped a product portfolio focused on flexibility, reliability and the specific needs of pharmaceutical manufacturers, laboratories and R&D environments.

Today, as part of Marchesini Group, Dott. Bonapace continues to develop its specialised technologies while benefiting from the broader expertise and international reach of the Group.

Meet Dott. Bonapace at CPHI Milan 2026

CPHI Milan will provide an opportunity for pharmaceutical manufacturers, R&D professionals and industry specialists to meet the Dott. Bonapace team and discover its technologies in operation.

CPHI Milan 2026
6–8 October 2026
Fiera Milano, Milan, Italy
Marchesini Group – Stand 9A2, Hall H09

Discover the machines, discuss your production requirements with our specialists and find out how Dott. Bonapace solutions can support your pharmaceutical manufacturing and R&D activities.

Learn more about Dott. Bonapace and our pharmaceutical machinery at CPHI Milan 2026.

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Dott. Bonapace & C. is proud to announce its participation in CPHI Milan 2026, one of the world’s leading pharmaceutical exhibitions, taking place from 6 to 8 October 2026 at Fiera Milano.

Hall H09 | Stand 9A2

This year’s edition will be particularly significant, as 2026 marks the 80th anniversary of Dott. Bonapace & C. For eight decades, we have been designing and manufacturing high-quality pharmaceutical process equipment, supporting pharmaceutical, nutraceutical, cosmetic, and healthcare companies worldwide with innovative, reliable, and tailor-made solutions.

Visitors to our stand will have the opportunity to experience our latest technologies in operation, meet our technical and sales teams, and discover how our equipment can improve efficiency, flexibility, and product quality across a wide range of pharmaceutical manufacturing processes.

Live Machines on Display

During CPHI Milan 2026, we will showcase a selection of our most advanced pharmaceutical machines, all available for live demonstrations:

• 3X-PACK – Automatic blister packaging machine for thermoforming, sealing, coding, and cutting.
• IN-CAP SE – Automatic capsule filling machine for powders, pellets, tablets, mini-tablets, liquids, and capsule-in-capsule applications.
• IN-CAP SE WIP with High Containment System – Our latest containment solution for the safe processing of highly potent active pharmaceutical ingredients (HPAPIs), combining capsule filling with advanced operator protection.
• CPR-22 – Rotary tablet press for single and double-layer tablet production, ideal for R&D, clinical batches, and medium-scale manufacturing.
• CPR-18 SE – High-performance rotary tablet press designed for pharmaceutical, nutraceutical, cosmetic, and industrial tablet production.
• BP-10 – Automatic filling machine for suppositories and vaginal ovules.
• BP-11 – Automatic sealing, coding, and cutting machine for suppositories and ovules.
• CU-1 – Compact cooling unit for controlled solidification of suppositories and ovules.

Our visitors will also discover how several of these machines can be integrated into complete production solutions. In particular, BP-10, CU-1, and BP-11 work together as a fully automated line for the production of suppositories and ovules, covering the entire process from filling and controlled cooling to final sealing, coding, and cutting.

Celebrating 80 Years of Excellence

Since 1946, Dott. Bonapace has continuously invested in research, engineering, and manufacturing excellence to develop pharmaceutical equipment that meets the highest standards of quality, precision, and regulatory compliance.

Today, our portfolio includes solutions for capsule filling, tablet compression, blister packaging, powder handling, containment systems, suppositories and ovules production, laboratory equipment, and customized pharmaceutical processing technologies.

CPHI Milan 2026 will be an opportunity not only to present our latest innovations but also to celebrate an important milestone together with customers, partners, distributors, and friends from around the world.

We look forward to welcoming you to Hall H09 – Stand 9A2, where you will be able to experience our technologies firsthand, discuss your production requirements with our specialists, and celebrate 80 years of Dott. Bonapace & C.

CPHI Milan 2026
6–8 October 2026
Fiera Milano, Italy
Hall H09 | Stand 9A2

See you in Milan!

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The TALLY automatic counting machine is a high-performance tablet and capsule counting machine designed for accurate bottle filling in pharmaceutical, nutraceutical, healthcare, and industrial packaging applications. Engineered for medium-scale production, it combines precision counting, reliable product handling, and easy integration into complete packaging lines.

The machine features two loading and unloading tables connected by a constant-speed conveyor, ensuring a continuous product flow and optimal bottle positioning throughout the counting process. This design maximizes production efficiency while maintaining exceptional counting accuracy for tablets, capsules, softgels, coated tablets, and other solid dosage forms.

Automated Counting and Bottle Filling Process

The fully automatic operating cycle guarantees fast, accurate, and repeatable production.

An empty bottle is automatically positioned beneath the counting head, where a dedicated sensor verifies its correct placement. Once detected, the counting system dispenses the programmed quantity of tablets, capsules, or pills with high precision. After filling, the bottle is automatically released and replaced by the next empty container, ensuring a continuous and efficient production cycle with minimal downtime.

Complete Pharmaceutical and Nutraceutical Packaging Line

The TALLY counting machine can be seamlessly integrated with automatic capping machines, labeling machines, and bottle handling systems to create a complete pharmaceutical bottle filling line or nutraceutical packaging line. Its modular design makes it the ideal solution for manufacturers seeking a scalable and flexible production system capable of handling a wide variety of products and bottle formats.

Whether you need an automatic tablet counting machine, a capsule counting machine, or a complete bottle filling system, TALLY provides the precision, reliability, and productivity required by today’s pharmaceutical and nutraceutical industries.

Advanced automated solution

Designed to streamline the packaging of tablets and capsules for the pharmaceutical and nutraceutical industries.
From product counting to the finished bottle, TALLY integrates every key step into one efficient workflow:
Accurate counting
Automatic filling
Reliable capping
Precise labelling

Discover the complete line:

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Advanced OEB5 Containment Solutions with the CPR-18 WIP Rotary Tablet Press

In today’s pharmaceutical industry, manufacturing environments must deliver more than high performance. Companies require flexibility, continuous operation, operator safety, ergonomic design, and strict containment control to comply with global regulations.

To meet these demands, modern production has evolved beyond traditional setups where machines are simply placed inside isolators. At Dott. Bonapace, we engineer fully integrated containment systems, where the isolator and the machine function as a single, optimized process unit—designed to achieve OEB5 / OEL <1 µg/m³ containment levels.

Native Isolator Integration for Pharmaceutical Equipment

Unlike conventional solutions, Dott. Bonapace machines are designed from the ground up for isolator integration, ensuring superior performance and compliance.

This approach guarantees:

• Seamless mechanical integration
• Complete functional synchronization
• Optimized layout and operator ergonomics

A key example is the CPR-18 WIP Rotary Tablet Press, a compact and highly efficient solution engineered for contained tablet compression. The same integrated concept can be extended to:

• Capsule filling machines
• Blister packaging lines
• Powder mixers and granulators
• Counting and checkweighing systems

Advanced Containment Technology for OEB5 Applications

Each containment system is designed with a comprehensive containment strategy to safely handle highly potent APIs.

Core features include:

• High-efficiency HEPA filtration systems
• Split Butterfly Valves (SBV) for safe powder transfer
• Integration with dedusters, metal detectors, and lifting systems

These solutions ensure maximum containment performance, while maintaining full validation readiness and compliance with pharmaceutical standards.

WIP (Wash-In-Place) System for Safe Cleaning

The integrated Wash-In-Place (WIP) system is essential for ensuring safety, efficiency, and contamination control.

The CPR-18 WIP tablet press is designed with:

• Dedicated containment-friendly construction
• Smooth, optimized surfaces for effective washing
• Easy access for maintenance and inspection

Cleaning is performed using:

• Spray balls and spray guns
• Integrated drying through process lines

All cleaning operations are executed without breaking containment, reducing downtime, improving operator safety, and increasing productivity.

Contained Product Transfer Systems

Safe material handling is critical in high-containment environments. The system supports multiple contained transfer technologies, including:

• RTP (Rapid Transfer Ports)
• Split Butterfly Valves
• Continuous liners and BIBO systems

This modular approach allows full customization based on process requirements while ensuring continuous containment integrity.

Centralized HMI and Data Integrity

The entire system is controlled through a single HMI interface, simplifying operations and ensuring data compliance.

Operators can:

• Monitor and adjust machine parameters
• Access real-time system status
• View alarms, trends, and process data
• Manage WIP cycles
• Ensure 21 CFR Part 11 compliance

This centralized control improves process visibility, validation, and operational safety.

CPR-18 WIP Rotary Tablet Press: Key Features

The CPR-18 WIP Rotary Tablet Press is designed for:

• R&D applications
• Clinical trials
• Small batch production

Main specifications:

• Three turret configurations available
• Maximum compression force: 60 kN
• Compatible with Euro B, D, and TSM tooling

Advanced digital controls and dedicated software enable precise parameter management and data analysis, making it an ideal solution for high-containment tablet manufacturing.

Benefits of Integrated Containment Systems

By adopting a fully integrated isolator-machine solution, pharmaceutical manufacturers gain:

• Greater process flexibility
• Enhanced production control
• Increased efficiency and productivity
• Maximum operator protection
• Fully customizable solutions

High-Performance Containment Solutions by Dott. Bonapace

Dott. Bonapace’s containment systems are engineered to meet the most stringent pharmaceutical requirements, combining innovation, safety, and compliance.

The CPR-18 WIP containment system represents a reliable and future-proof solution for companies handling highly potent compounds and seeking top-level containment performance.

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Modern pharmaceutical production environments demand far more than performance alone. Today’s manufacturers require batch flexibility, operational continuity, safety, ergonomics, and above all, containment—to protect both operators and the surrounding environment.

For this reason, the industry has moved beyond the traditional concept of a machine placed inside an isolator. At Dott. Bonapace, we design fully integrated containment systems, where the isolator and machine operate as a single, unified process organism, engineered to meet the highest pharmaceutical standards and reaching the OEB5/OEL<1μg/m3 standard.

Machines Natively Designed for Isolator Integration

Dott. Bonapace machines are designed from the ground up to operate inside isolators, not adapted after installation. This design philosophy ensures seamless integration at every level:

• Mechanical integration
• Functional integration
• Optimized layout and ergonomics

Key solutions include the IN-CAP WIP capsule filling machine and the CPR-18 WIP rotary tablet press. The same concept can be extended to additional pharmaceutical equipment such as blisters, mixers, counting systems, checkweighers, and granulators.

Advanced Containment and Functional Integration

Each integrated system is engineered with a clearly defined containment strategy, including:

• HEPA filtration systems
• Split Butterfly Valves for powder charging and discharge
• Integration readiness for dedusters, metal detectors, and lifters

These components can be supplied directly or coordinated with the end user, ensuring that every system meets specific process and containment requirements while maintaining validation readiness.

WIP (Wash-In-Place) Logic for Safe and Efficient Cleaning

The WIP (Wash-In-Place) logic is one of the core strengths of the system. Machines are designed with:

• Dedicated containment features
• Surfaces and internal geometries optimized for washing
• Easily accessible components for maintenance

Cleaning is performed using spray balls and spray guns, with drying through the same process lines. All operations are carried out without any loss of containment, ensuring faster cleaning cycles, improved safety, and higher operational efficiency.

High-Containment Product Transfer Solutions

Product transfer is fully contained and can be performed using:

• RTP (Rapid Transfer Ports)
• Split Butterfly Valves
• Continuous liners or BIBO systems

The system is modular and open to integration with additional transfer technologies, depending on customer needs or specific process requirements, while always guaranteeing containment continuity.

Centralized Single HMI and Data Integrity

One of the most important features of the integrated system is management through a single HMI. From one centralized interface, operators can:

• Set and monitor machine parameters
• Check system status in real time
• View alarms and trends
• Manage WIP cycles
• Ensure compliance with 21 CFR Part 11

This unified control provides complete visibility of the entire process, making the system simpler to operate, easier to validate, and significantly safer.

IN-CAP WIP Capsule Filling Machine

The IN-CAP WIP is an automatic capsule filling machine designed for high-containment environments. It supports dosing of:

• Powders
• Pellets
• Single tablets and mini-tablets
• Capsule-in-capsule
• Liquids

The machine is compatible with all capsule sizes (000 to 5, including DB Caps) and offers independent, double, or triple station configurations. With over 20 filling combinations available, including patented double powder dosing, IN-CAP WIP delivers exceptional flexibility for pharmaceutical production.

Overall Benefits of Integrated Containment Systems

By adopting an integrated isolator–machine approach, pharmaceutical manufacturers benefit from:

• Greater operational flexibility
• Enhanced process control
• High efficiency and productivity
• Superior operator safety
• Customizable solutions tailored to specific processes

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During the live, we showcased IN-CAP WIP, capsule filling machine, and CPR-18 WIP, rotary tablet press, both equipped with containment systems, highlighting advanced solutions that meet the highest industry standards while enhancing performance, safety and reliability in pharmaceutical manufacturing.

Special thanks to Marchesini Group for their support.

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